Sentence examples for binding to bone from inspiring English sources

Bmp15 induces transcription of Inhibitors of DNA Binding proteins (Idb1-3) via binding to Bone Morphogenetic Protein Receptor type I (Bmpr1a), and the downstream transportation of Smad-complex (Madh8-Madh4) thethe nucleus[ 52, 53].

Note in (a) the absence of unspecific Ab binding to bone tissue and to hematopoetic cells, in (b) the absence of unspecific Ab binding to granulocytes and monocytes and in (c) the absence of unspecific Ab binding to granulocytes and megakaryocytes.

This effect may be mediated via C3a binding to bone marrow dendritic cells, since inhibition of such binding impairs T cells response to antigen presented by those cells 10].

Calcification inhibitors such as matrix GLA protein (MGP) may restrain AC by binding to bone morphogenic proteins (BMP-2) [ 25].

After binding to bone mineral, they are taken up selectively by the osteoclasts and inhibit the essential enzyme FDPS (farnesyl diphosphate synthase).

Our assays focused upon cysteine adducts that accounted for 38 to 45% of protein binding to Hb and 63 to 81% of protein binding to bone marrow.

In order to assess the ability of HPMA copolymer-ALN-TNP-470 conjugate to bind to bone mineral its binding potency to HA was evaluated.

This increases the amount of drug that binds to bone and is likely to minimize the amount of drug that diffuses from bone after binding.

Bisphosphonates target the underlying cause of skeletal morbidity by binding to the bone surface and inhibiting osteoclast-mediated bone resorption.

It was reported that bone density and the ratio of cortical bone and cancellous bone have influence on the primary stability of an implant and that higher primary stability is achieved with thread, even at the slightest level, binding to cortical bone rather than being surrounded by only cancellous bones [32].

All bisphosphonates contain a phosphorus carbon phosphorus central structure that promotes their binding to the bone matrix, and variable side chains that determine the specific effects on bone cells.