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This provides evidence that the effect of 14-3-3β 14-3-3β 14-3-3βony is specellc to binding and inhibition of Rnd3 and not due to binding to another cellular target.
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Most neurotransmitters are polar organic compounds that exert their signaling effect by binding to cellular receptors located at the cellular membrane.
Passive immunisation with antibodies binding to the cellular prion protein (PrPC) can protect against prion disease.
However, there was no data to demonstrate whether LANA can also regulate cellular gene expression by binding to the cellular chromosome DNA.
For example, an antibody to PA could prevent this protein from binding to its cellular receptor.
The fiber knob domain mediates the initial virus-cell interaction by binding to a cellular receptor.
This is a good system to screen for compounds that may have non-specific binding to other cellular proteins.
Fyn, in turn, was found to be activated by oligomeric amyloid beta binding to the cellular prion protein [ 205].
It is likely that all native Nde1 molecules are fully occupied through binding to other cellular proteins.
However, E6 thwarts this response by binding to the cellular E6-Associating Protein (E6AP) and targeting p53 for degradation.
Viral membrane fusion proteins are responsible both for binding to cellular receptors, and the subsequent fusion of viral and cellular membranes.
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