Sentence examples for binding to and regulating from inspiring English sources

The proton pump, vacuolar H+ ATPase (V-ATPase), relays this 'inside-out' amino acid signal by binding to and regulating the Rag GTPases and Ragulator [Zoncu R. et al, Science (2011)].

OSBP functions as a cholesterol sensing scaffolding protein that may regulate ERK1/2 activity by binding to and regulating the tyrosine and threonine phosphatases that act on the T184 and Y186 sites on ERK2[30].

In any model presented, BubR1 plays a central role in binding to and regulating the APC/C Cdc20 complex.

They exert their effects largely by binding to and regulating the activity of transcription factors of the nuclear receptor superfamily (Wollam and Antebi 2011).

These data indicate that p53 may modulate either DNA repair or apoptosis by binding to and regulating the activity of the TFIIH-associated DNA helicases.

Moreover, it also stabilizes kinetochore microtubule attachments and serves as a sensor of SAC by binding to and regulating the activity of BubR1.

LIN28 is a RNA-binding protein that binds to and regulates both mRNAs and miRNAs.

(d) the transcript may acquire trans functions such as binding to proteins and regulating their activity, sponging microRNA or binding to chromatin at distal locations.

This gives a more complete view of a TF binding to and possibly regulating a target gene.

Previous studies suggest that Lola may execute its function by directly binding to DNA and regulating the expression of the target genes.

The RGD motif enables ligand binding to integrins and regulates cell growth, migration and survival [ 26].