Sentence examples for binding to a subunit from inspiring English sources

One antibiotic, rifampin, interferes with ribonucleic acid (RNA) synthesis in bacteria by binding to a subunit on the bacterial enzyme responsible for duplication of RNA.

Compounds from this family are shown to potently inhibit cyclin-dependent kinases by competing with ATP for binding to a catalytic subunit of the protein.

The enzymatic activity of cdk5 is mainly regulated by its binding to a regulatory subunit (p35, p25 or p39).

These kinases are DDKs (Dbf4-dependent kinases), so called because they are activated by binding to a regulatory subunit (Dbf4p in S. cerevisiae), and they play a fundamental role in the activation of licensed replication origins [ 78].

EIF2S3 has been described to contribute to the early stage of protein synthesis by interacting with guanosine-5′-triphosphate and initiator transfer RNA to form a ternary complex and binding to a 40S ribosomal subunit (Entrez Gene: EIF2S3).

In naïve T cells, surface CTLA4 expression is inhibited by rapid endocytosis resulting from CTLA4 binding to AP50, a subunit of the clathrin adaptor AP-2 protein [2].

Serial reintroduction of five sites failed to reestablish Sic1 binding

For example, autophagy induction triggers activation of the RalB GTPase and binding to Exo84, a subunit of the exocyst complex.

Upon ligand binding to a GPCR, the α subunit dissociates from the Gβγ heterodimer, resulting in the activation of various signaling cascades (reviewed in [ 14, 15]).

Nicotine can mimic the actions of acetylcholine as an agonist by binding to the a subunits of nAChRs [20].

Taken together, these results indicate that nucleotide analogs induce SpoIIIE pausing by binding to a subset of ring subunits and arresting them in a pre-hydrolysis state.