Sentence examples for binding to a structural from inspiring English sources

Moreover, the screening of these SCF clones for binding to a structural antibody helped identify mutations that result in small or large conformational changes in SCF.

Indeed, a positive antigen-binding signal probably reflects a collective mixture of polyclonal and cross-reactive serum antibodies binding to a variety of structural epitopes exposed by each spotted antigen.

At the heart of the screening for fragments binding to a specific target, crystallography delivers structural information essential for subsequent drug design.

Notably, DUF630 is suggested to be involved in nucleic acid binding according to a structural modeling study (Rigden 2011).

Furthermore, as in EO, matrix receptors binding to the structural components of the ECM have an impact on chondrocyte behavior in articular cartilage.

Therefore, while biochemical studies have indicated an important functional role of HRMs as a redox switch that regulates heme binding to the enzyme, a structural perspective of this redox-dependent differential regulation of substrate (heme) binding to HO2 was missing.

The characterization of the non-canonical EF1 and canonical EF2 reveals that Ca2+ binding to NCaBD induces a structural change as observed in the enhancement of Trp fluorescence and the increase of α secondary structure.

It is a matricellular glycoprotein that may modulate cell interaction within the ECM by binding to both ECM structural components and growth factors.

By binding to structural proteins such as collagen type I, SPARC regulates cellular interactions with the extracellular matrix [ 21].

Moreover, we have demonstrated that both Armet and Creld2 have substrate specificity in their binding to structural proteins and that Creld2 possess PDI-like activity.

The binding of specific ligands leads to a structural reorganization of the cytosolic TIR domains, which is used as a signaling platform for adaptor recruitment.