In mammalian cells, HCF-1 appears to promote G1-S phase progression by binding to E2F1 via a so called HCF-1 binding motif or HBM.
Unlike most targets, 14-3-3s activate the plant plasma membrane H+-ATPase by binding to a so-called C-terminal mode III binding motif SW pT X-COOH in which the phoSW pT X-COOHresinue is the penultimate threonine residue in the C-terminal autoinhibitory domain [ 15].
In UK, for instance, caller first have to talk to a so called call-handler, how then might transfer the call to a RN, if deemed appropriate.
We made use of a so called probability wheel as a visual aid to the respondents.
To obtain binding of neutrophils to the vascular endothelium, β2-integrins must be turned into an active state; a process accomplished via receptors for chemokines and chemotactic factors by a so called inside-out signalling [15].
In contrast, the second structure determined for this family PepTSt, was captured in the fully open state, with the binding site accessible to the cytoplasmic side of the membrane — a so called inward open state (PDB: 4APS).
Erivedge works to inhibit the so-called Hedgehog signaling pathway by binding to a protein called Smoothened.
Importantly, this definition excludes potential binding sites that have not been demonstrated to bind ligands (so called unliganded binding sites), thereby creating a bias towards currently exemplified protein ligand complexes.
Another retinoid, 9-cis-RA presents a similar affinity in its binding to both receptors, while the so called rexinoids are able to differentially activate RXRs.
These proteins are widespread in all three domains of life and their Zn-binding motifs (in particular, so called "zinc fingers") are homologous [ 210].
We decided to compare the so called mappability to a RNA-seq data set.
