Sentence examples for binding to a small from inspiring English sources
The antibiotic gentamicin, which inhibits protein translation by binding to a small subunit of bacterial ribosomes and not to eukaryotic ribosomes, did not affect cluster formation efficiency.
Monoubiquitin signals are transmitted by binding to a small but rapidly expanding class of ubiquitin binding motifs.
Cavities with physicochemical properties that are consistent with binding to a small molecule that is not necessarily RO5-compliant are classified as druggable (or tractable) according to the relaxed model.
Since the activity of CtBP is, itself, governed by the processing of calorie-rich molecules, the more of those molecules the body processes, the more at risk of cancer it becomes.Previous work has shown that CtBP senses the amount of energy in a cell by binding to a small molecule called NADH.
These features can be utilised in the construction of biosensors for a wide range of target compounds as, in principle, any regulatory protein whose activity is modulated by binding to a small molecule can have its effector/inducer profile artificially altered.
Immunohistochemistry for fibrinogen revealed, in naïve and immune challenged colonies alike, specific antibody binding to a small population of Botryllus compartment cells.
The chelator EGTA is used as a masking agent that prevents Zn2+ binding to a small-molecule fluorescent Zn2+ reporter such as PAR.
The BMCC1 C-terminal isoform BNIPXL binds to a small GTP-binding protein RhoA and Lbc, a RhoA-specific guanine nucleotide exchange factor (RhoGEF), through its BCH domain, leading to the inhibition of RhoA-dependent stress fiber formation and malignant transformation.
In eukaryotes this structure involves DNA binding to a complex of small basic proteins called histones, while in prokaryotes multiple types of proteins are involved.
General anaesthetics are much more selective than is usually appreciated and may act by binding to only a small number of targets in the central nervous system.
βPFTs are secreted as soluble monomer proteins, which, after binding to a receptor (protein or small molecule) at the cell surface, oligomerize and undergo significant conformation change such that each monomer extends a β-hairpin that contributes to the formation of the β-barrel pore.
