Sentence examples for binding to a single from inspiring English sources

Lectin binding to a single saccharide ligand is typically a low-affinity interaction.

For the kinase PDK1, Tethering identified ligands that activated or inhibited enzymatic activity by binding to a single allosteric site.

They consist typically of metal centers onto which is bound organic donor molecules (ligands) that, rather than binding to a single metal centre, bridge these metal centers to afford coordination polymers.

Several possible explanations for the optimized variants binding to a single additional off-target protein exist.

The high correlation coefficient of hyperbolic curve fitting (R2 = 0.9775) is consistent with binding to a single class of receptors.

From this result, the increased TNF1-opt E.coli lysate binding observed on the microarray appears to be due primarily to enhanced binding to a single E.coli protein.

Slit acts by binding to a single-pass transmembrane protein Roundabout (Robo).

FBP1 was first identified as a DNA-binding protein that regulates the expression of c-Myc by binding to a single-stranded FUSE located upstream of the c-Myc promoter FBP1 is also an RNA-binding protein that binds to the Hepatitis C and Enterovirus 71 RNAs and mediates their replication during retroviral infection.

Briefly, antigen-antibody binding reactions (shown in Figure  4) include: a free antibody binding to a free antigen creating a single-bound antibody; a single bound antibody binding to a free antigen creating a double-bound antibody; the removal/clearance of a single-bound antibody; and the removal/clearance of a double-bound antibody.

Thus, the tests require (i) well-characterized transcription factor binding specificity and (ii) confident alignment of a binding site to a single specificity matrix.

At the molecular level, log dose response curves are typically sigmoidal because the response is the result of the ligand binding (reversibly) to a single receptor site and thus directly proportional to receptor binding (law of mass action; Balakrishnan, 1991).