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It is now widely accepted that FC activates the H+-ATPase by binding to a regulatory protein belonging to the 14-3-3 14-3-3 14-3-3 association with a specifamilynding sequence located at the end of the C-terminal autoinhibitory domain of the PM H+-ATPase releases the autoinhibitory action (Beffagna and Lutzu 2007).
The enzymatic activity of cdk5 is mainly regulated by its binding to a regulatory subunit (p35, p25 or p39).
Recently, Eiring et al. reported that miR-328 can act as a decoy by binding to a regulatory RNA binding protein and preventing it from blocking translation of mRNAs [18].
Transcription factor binding to a regulatory DNA element usually results in repositioning of nucleosomes.
This model of expression regulation can also be derived from a thermodynamic model of two transcription factors (a repressor and an activator) independently binding to a regulatory region.
CIC is a downstream component of receptor kinase (RTK) pathways (RTK RAS RAF MAPK) and blocks transcription through binding to a regulatory region.
Similar(50)
Notably, 6ZFP-mediated perturbation of EBF1 binding to a Gata3 regulatory region restored Gata3 expression, abrogated EBF1-driven suppression of T cell differentiation, and prevented B cell differentiation via a GATA3-dependent mechanism.
Surprisingly, we observed that ligand (T3) weakens TR binding to a negative regulatory element (NRE) present in the TSHβ promoter.
Therefore, a simple association of TAL1 peaks to their closest genes may miss target genes regulated by TAL1 via binding to a distal regulatory element.
Splicing factor SRSF1 was previously shown to regulate RON exon 11 by binding to a downstream regulatory element on exon 12 (Ghigna et al, 2005).
Specifically, we showed that the introduction of H3K9me1 was a consequence of the repression of early transcription by the product of transcription, T-antigen, binding to a critical regulatory sequence known as Site I [ 8].
More suggestions(17)
binding to a single
binding to a complementary
binding to a putative
binding to a wide
binding to a small
binding to a light-reactive
binding to a structural
binding to a cysteine-rich
binding to a foreign
binding to a neuronal
binding to a nucleosome
binding to a particular
binding to a human
binding to a monoclonal
binding to a nearby
binding to a same
binding to a canonical
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