Sentence examples for binding to a putative from inspiring English sources

We then asked whether 17B1.3 prevents signaling by binding to a putative site for B7-H6 dimerization.

The bait plasmid pH3U3-p01 carrying the deletion fragment of pfk-pyk promoter captured catabolite control protein A (CcpA) which could regulate the expression of pyk by binding to a putative catabolite-responsive element (5′-TGTAAGCCCTAACA-3′) upstream the -35 region.

The factor was isolated biochemically from growing cells, guided by its specific binding to a putative transcription regulatory element, the C-module, within the D. discoideum retrotransposon TRE5-A [6], [7].

In this context, we have been unable to reproduce the reported results supporting the notion that recombinant visfatin may act as an extracellular pro-inflammatory cytokine through binding to a putative receptor on human PBMCs, even at doses above the physiologocal levels (results not shown).

RCAS1 induces apoptosis of lymphocytes by binding to a putative RCAS1 receptor (Nakashima et al, 1999).

There are two possibilities: First, the carbohydrate side chains may participate directly in ligand binding to a putative fibroblast receptor.

A de novo drug design methodology was used to generate an initial set of structures that could potentially bind to a putative binding site.

Second, the biofragment library is screened (fragment-based screening cascade) for binding to a novel putative ligand-binding protein from that class.

Second, the library can be screened for binding to a novel putative ligand-binding protein from the same or similar class, and the characterization of hits provides insight into the basis of ligand recognition, selectivity, and function at the substrate level.

Interestingly Kirchhoff et al. did report on the in vitro and in vivo formation of IRF-1 homodimers(28) for which it was difficult to reconcile the role of this homodimer in binding to a single putative IRF-1 binding site; perhaps instead the homodimer plays a more specific role in the promoters of genes that contain tandem repeat IRF-1 binding sites rather than single sites.

Moreover, although plg displays widespread cell-surface binding to a range of putative receptors, it is the uPA-co-localised fraction of plg that is readily activated to pln [ 28].