Sentence examples for binding to a protein from inspiring English sources

HDV and HBV infect the liver by binding to a protein called NTCP that is present on the surface of liver cells.

Erivedge works to inhibit the so-called Hedgehog signaling pathway by binding to a protein called Smoothened.

Despite this, few options are available to directly measure a compound binding to a protein within the more complex cellular and in vivo systems to which they will ultimately be applied1.

It does so by binding to a protein called PD-1 on a subset of immune cells (T cells) and dampening their response to signals calling for growth and activation.

Once at the tumor, this first wave of particles provokes the body into believing that an injury has occurred at a tumor site, either by emitting heat or by binding to a protein that sets off the coagulation cascade.

AMG 145 works differently than statins by binding to a protein called PCSK9, which assists in the turnover of LDL cholesterol receptors that help clear LDL from the blood.

Affinity purification was performed by binding to a Protein-G column followed by elution of the bound antibody with glycine buffer (pH = 3.0) and subsequent dialysis against PBS (pH7.2 7.4).

For instance, the presence of R435 in IgG3 (and H435 in the other IgG subclasses) has been implicated to result in IgG3-specific properties related to binding to protein A, protein G and the neonatal Fc receptor (FcRn).

Six years ago, Bonifacino and colleagues found that Nef does this by directly binding to a host protein, AP2, that latches onto a protein called clathrin.

How proteins achieve high-affinity binding to a specific protein partner while simultaneously excluding all others is a major biological problem that has important implications for protein design.

DARPins are a novel class of proteins selected for specific, high-affinity binding to a target protein.