Sentence examples for binding to a partner from inspiring English sources

These short order-prone segments might correspond to Molecular Recognition Elements (MoREs), where these latter are short order-prone regions within IDRs with a propensity to undergo induced folding (i.e. a disorder-to-order transition) upon binding to a partner.

Small hydrophobic clusters occurring within mainly disordered regions, as observed in HCA plots, were assumed to correspond to putative Molecular Recognition Elements (MoREs), where these latter are short order-prone regions within IDRs that fold upon binding to a partner or ligand [60], [61], [62], [63].

Here, the IDR acts as a competitive inhibitor of other regions in the same protein for binding to a partner.

It is therefore possible that it is exported from the nucleus by binding to a partner that possesses a NES (Summary in Figure 2).

The simplest model would be that phosphorylation either promoted or inhibited binding to a partner, but this is evidently not the mechanism in play here.

In general, transport or localization of a protein to its subcellular compartment is facilitated either by binding to a dedicated receptor via a signal sequence, following which the receptor shuttles the molecular "cargo" into or out of a specific subcellular compartment, or indirectly via binding to a partner protein.

Af9 interaction with partnering proteins appears to be mediated by an intrinsically disordered domain that assumes different conformations depending on the binding partner, thereby limiting binding to a single partner at any time [ 29].

Since the property of binding to a WT partner is not shared among the IDH mutants, it is unlikely that binding to a WT partner is an important feature of the IDH mutations in driving cancer pathogenesis.

Another interpretation of our results is that the peptide exerts its inhibition by inhibiting folding or binding to a chaperone partner.

Apart from this role in cuticle formation, many roles were proposed for LTPs including systemic resistance signaling [ 51], ability to promote cell wall expansion through binding to a hydrophobic partner in cell walls [ 52], and activation of a PG [ 53].

MoRFs are short order-prone motifs flanked by disordered regions that are involved in molecular recognition and are able to undergo disorder-to-order transition during binding to a specific partner.