This gene is known to upregulate −P stress-related genes such as high-affinity Pi transporters, RNases, and acid phosphatases by binding to an imperfect palindromic sequence (P1BS, GNATATNC) in the promoter regions (Rubio et al. 2001).
PHR1 also upregulates many responsive genes that are expressed under −P stress, including those encoding high-affinity Pi transporters, RNases, and acid phosphatases, by binding to an imperfect palindromic sequence (P1BS, GNATATNC) in the promoter regions of these genes (Rubio et al. 2001).
Transcriptional initiation from AR-TIS I is dependent on sequences located between positions -17 and +45 and initiation from AR-TIS II facilitated by a palindromic homopurine repeat and SP1 binding to a GC-box [ 12, 13].
The Cyclic-AMP response element (CRE) binding protein (CREB) binds preferentially to a palindromic sequence (TGACGTCA), known as the canonical CRE, and also to other CRE variants.
TtgR binds to a pseudo-palindromic site that overlaps the ttgR/ttgA promoters.
Regulation of transcription can occur through binding to consensus palindromic sequences in the DNA, known as Hormone Response Elements (HREs), or alternatively through protein-protein interactions in a manner that is independent of direct DNA binding [4].
Apparently, DSXF1 activates vg expression while DSXM1 represses vg expression by binding to the palindromic core sequence (ACATTGT) in the promoter region of vg [ 71, 72].
Mnt binds as a tetramer to a palindromic binding site.
Recent evidence in E. coli found that MlrA directly binds to a 33 bp palindromic sequence between IHF- and OmpR-binding sites in the upstream sequence of the csgD promoter.
