Sentence examples for binding to a negative from inspiring English sources

Surprisingly, we observed that ligand (T3) weakens TR binding to a negative regulatory element (NRE) present in the TSHβ promoter.

This same complex inhibits IFN γ production through binding to a negative response element and interaction with an upstream enhancer element [ 47].

The term "negative regulation" has been used in the context of nuclear receptor signalling to describe the ability of NRs to down-regulate transcription of a target gene via binding to a potential "negative response element" or "negative regulatory element (NRE)".

As exemplary shown for cell line L428 in Figures 3a and b, both wild type and mutant specifically bind to the target cells and do not exhibit unspecific binding to a CD30-negative cell line, HL60.

This peptide was derived from BECN1 and fused to the HIV Tat protein transduction domain; it functions by binding to a newly identified negative regulator of autophagy known as GLIPR2/Gli Pathogenesis-Related 2, and relieving autophagy suppression.

However, p53 phosphorylation prevents p53 from binding to its negative regulator MDM2 [ 35].

Five of the identified TG2 peptide substrates that did not contain any known T-cell epitopes had sequences suggesting potential binding to HLA-DQ2.5 (a negative charge in one of the anchor positions P4, P6 or P7 [4]–[6]; no proline residues in positions P2, P4, P7 or P9 [14]).

On the contrary, early origins are depleted of K36me3 and this modification decreases around the time of Cdc45 binding to origins, pointing to a negative role of this modification.

Binding to positive glucocorticoid response elements as a homodimer results in transcriptional activation; and binding to negative glucocorticoid response elements results in transcriptional inhibition [ 26].

Specific (circle) and non-specific binding (triangle) (binding to negative control Colo16 cell line) of 125I-chAb 14C5 (a), of 125I murine Ab 14C5 (b), of 125I-chF ab' 2 125I-chF ab' 2of 14C5-chFand14C5 (d).

Figure 10 illustrates SEB binding to negative control electrodes that lacked capture Ab and were blocked with casein.