Sentence examples for binding to a membrane-spanning from inspiring English sources

Like other cytokines IL-6 acts by binding to a membrane-spanning receptor.

For this, we used the HaloTag protein (Promega Corp ., which is a genetically modified hydrolase that is able to catalyze its covalent binding to a series of membrane-spanning ligands and can be used for in vivo labeling [15].

Each half transporter consists of a nucleotide binding domain and a membrane-spanning domain, and heterodimerization of PatA and PatB is required to form a functional transporter (5).

The second system was to use palladium II) to bring together two "halves" and create a membrane-spanning lipid that might further assemble to produce a membrane pore.

The remaining transport systems are ABC-type carriers, consisting of a membrane-spanning permease and an ATP-binding subunit.

NADPH oxidases are enzyme complexes with a membrane-spanning catalytic NOX subunit, which depends to varying degrees on other subunits.

MUC16 is a membrane-spanning mucin and the largest mucin known to date.

EGFR is a membrane-spanning cell surface receptor and consequently links internal signaling pathways to the extracellular environment [ 19].

BmStart1 contains a membrane-spanning MENTAL domain in its N-terminus and a lipid-binding START domain in its C-terminus.

The bacterial Trk potassium transport system consists of a membrane-spanning protein (TrkH), constituting the translocating subunit, and a peripheral membrane-associated nucleotide binding protein (TrkA), required to energize the system [32].

Insulin signalling is initiated by binding of insulin-like hormones to surface receptor tyrosine kinases of the insulin/insulin-like growth factor (IGF) family that are usually produced as long pro-peptides which are later processed into an extracellular α-subunit and a membrane-spanning β-subunit, connected by a disulphide bridge [ 7- 9].