Sentence examples for binding to a high from inspiring English sources

IL-15 mediates its biological effects by binding to a high affinity heterotrimeric receptor complex which is comprised of IL-15Ralpha, IL-2/15Rbeta and IL-Rgamma.

Ivermectin is thought to have an allosteric mode of action by increasing maximum current when binding to a high affinity site on the receptor to stabilise the open state, whereas binding to a low affinity site is proposed to slow the rate of deactivation [ 44].

Circular β2GPI can be converted to an extended form by altering pH and salt concentrations, binding to a high-affinity antibody directed to domain I or by the binding to cardiolipin [11].

These data suggest the possibility of HNE reversibly binding to a high-affinity target associated with IL-1β inhibition.

This peptide was initially identified by its ability to compete with thrombin for binding to a high-affinity thrombin receptor on fibroblasts and to generate receptor occupancy-dependent mitogenic signals.

Antibody binding to a high-entropy molecule would require a greater activation energy than binding to a lower-entropy molecule and may thereby introduce structural or functional constraints in either the FWR or CDRs.

Vitamin D is a steroid hormone that exerts most of its biological activities by binding to a specific high-affinity receptor, the vitamin D receptor (VDR).

Vitamin D exerts most of its biological activities by binding to a specific high-affinity receptor, the Vitamin D Receptor (VDR), that was first identified in a breast cancer cell line in 1979 [ 10].

SPR studies demonstrated that the avidity effect of OMAB induced a very strong binding to, and a high selectivity for, Aβ oligomers.

Humanised PR1A3 showed specific binding to MKN45, a high CEA-expressor.

However, ATR neither enhanced nor repressed DNA binding activity to a high affinity SF-1 binding site (Fig S3B).