Sentence examples for binding to a docking from inspiring English sources

Usually, either a small degenerate sequence or a conserved motif (PxIxIT) in the interacting protein directs binding to a docking site on the surface of the phosphatase distinct from the active site (Roy and Cyert 2009).

Vasquez and co-workers have used a similar approach to bias toward the identification of inhibitors binding to a scaffold docking site in JNK.

The positively charged D-domain is essential for MEK binding to a complementary acidic common docking domain in the carboxy-termini of ERK1 and ERK2 [ 20, 21].

Docking describe ligand binding to a receptor through noncovalent interactions which is commonly used to explore the ligand recognition on targets for new drug development [20].

We conclude that Msk1-mediated phosphorylation of H3S28 impairs PRC2-Ezh2, but not PRC2-Ezh1 binding to its docking site, H3K27me3.

Upon the binding of the target to a docking domain, the substrate is positioned within the catalytic site.

Depending on this standpoint, we firstly screened PMS targeted binding to MMP9 via docking calculation (Fig.  1b).

Each compound in the library is virtually docked into the target binding site through a docking program, which computationally models the ligand target interaction to achieve an optimal complementarity of steric and physicochemical properties.

Moreover, using a binding assay and a docking, we showed that delphinidin fits on ERα's activation site.

177 binding modes with a docking score lower than −20 were shown.

Moreover, molecular docking studies also indicated binding to the topoisomerase enzyme (PDBID 1ZXN).