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Due to their small size, avimers often consist of multiple A-domains with each binding to a different site on the target.
Taken together, this finding suggests that the transactivation of the TFAP2A promoter by NR2F2, RXRA and RARA could be due to binding to a different site than that previously described for steroid hormone binding or to an interaction of NR2F2 with components of the basal transcription machinery.
The lack of the DR1 motif in the remaining peaks may indicate that TR4 associates with some sites only indirectly by binding to a different transcription factor.
Two monoclonal antibodies targeting the extracellular domain of ERBB2 receptor with different mechanisms of action, one binding to a different epitope and the other conjugated to a cytotoxin, have recently been approved for clinical use (Baselga et al, 2012).
Latrunculin B increases the level of actin monomers by binding to a different site on G-actin, the nucleotide-binding cleft, and does not interfere with binding at the hydrophobic cleft.
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To improve preimplantation genetic diagnosis (PGD) accuracy by using "no result rescue" (NRR) consisting of the reanalysis of dubious results with additional probes binding to a locus different from the one previously analyzed.
Therefore, we can not exclude the possibility that the paralogous copies of S4 in Clostridia are regulated by Zur binding to a motif different from any in our profile.
In contrast, HME1 cells with transiently overexpressed wt p53 (Ad5WT) exhibited significant binding to a variety of different gene promoters.
This type of analysis has been previously applied to SPR analysis of IgM binding (Cooper and Williams, 1999) as well as analysis of pentavalent cholera-toxin binding to a number of different gangliosides (Kuziemko et al., 1996).
Most of these activities are known to be stimulated by binding to a number of different integrins via the RGD sequence (αv β3, αv β1, αv β5) or via RGD-independent interactions (α4 β1, α9 β1, and α8 β1).
Like many other flexible proteins in biology, members of the SIBLING family are thought to function by binding to a number of different proteins using short motifs that remain conserved while many of the intervening amino acids are permitted to change with time.
More suggestions(16)
binding to a potential
binding to a specific
binding to a specialized
binding to a single
binding to a regulatory
binding to a putative
binding to a Rho-type
binding to a small
binding to a light-reactive
binding to a hydrophobic
binding to a human
binding to a representative
binding to a nearby
binding to a magnetic
binding to a novel
binding to a palindromic
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