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Exact(14)
Moreover, RCL appears to mediate binding to a cell surface receptor that promotes cell adhesion to type I collagen and fibronectin [12, 13].
Our targeting system is based on Ad vector targeting via scFv-mediated binding to a cell surface molecule.
There was little to no binding to a cell line (A431) that lacked NgR, although the 431 cells were readily stained with a positive control, an anti-EGFR aptamer (Figure S4).
Adenomatous polyps are thought to be precursors to CRC whereas hyperplastic polyps are not [31], [32], suggesting that the target peptide could be binding to a cell surface target unique to dysplastic and/or cancerous cells.
These mutants were defective in binding to a cell line stably transfected to express αvβ3 as compared with WT bacteria.
Calcium exerts its effects on the parathyroid gland through binding to a cell surface receptor, the calcium-sensing receptor.
Similar(46)
These results indicate that B7-DC XAb modulation of DC phenotypes is through its ability to indirectly recruit common signaling molecules and elements of their endogenous signaling pathways through targeted binding to a cell-specific surface determinant.
Thus, two possible modes of action for such an antibacterial molecule can be underlined (i) competitive binding to a cell-surface exposed receptor (e.g. such as porin)[6], [10] involved in key cellular processes and (ii) channel or pore formation in the cytoplasmic membrane.
This key cell signalling pathway is activated by ligand binding to a cell-surface receptor tyrosine kinase (RTK), which in turn activates RAS.
Cell signaling pathways are sequences of biochemical reactions that propagate an input signal, such as a hormone binding to a cell-surface receptor, into the cell to trigger a reactive process.
Typically, ligand-binding to a cell surface receptor induces a wave of tyrosine phosphorylation (autophosphorylation in the case of receptor tyrosine kinases, or phosphorylation by receptor-associated kinases if the receptor itself lacks catalytic activity) resulting in the generation of phosphotyrosine binding sites for adaptor proteins such as growth factor receptor-bound protein 2 (GRB2).
More suggestions(16)
binding to a receptor
binding to a protein
binding to a subset
binding to a set
binding to a coupler
binding to a creation
binding to a range
binding to a ligand
binding to a magnet
binding to a fiber
binding to a promoter
binding to a lipid-water
binding to a peptide
binding to a surface
binding to a consensus
binding to a variety
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