Sentence examples for binding to a canonical from inspiring English sources

Both regions are necessary for high-affinity binding to a canonical W-box motif containing a consensus sequence (C/T TGAC(C/T).

TBP binding to a canonical TATA box proceeds via a two-step pathway; first an unstable complex with unbent DNA is established.

We have shown that a proven τ-phosphohistidine mimic is capable of sequence-specific binding to a canonical phosphotyrosine-binding domain.

Reduced spreading/mechanical force induced transcription factor c-Jun and its binding to a canonical AP-1 binding site in the MMP-1 proximal promoter.

It has been shown that, whereas the ATPase activity of SWR1 is enhanced upon binding to a canonical nucleosome, which we used in our study, it achieves the highest level of stimulation when the second substrate, the H2A.Z/H2B dimer, is also bound (Luk et al., 2010).

Figure  5 presents an example of C/EBPβ binding to a methylated canonical C/EBP motif (TTGC|GCAA).

In a cell-free system, C-1311 prevented HIF-1α from binding to an oligonucleotide encompassing a canonical HRE, but did not directly interfere with HIF-1α protein production.

The single-peptide binding mode follows a canonical ligand binding mechanism, i.e., binding to an open cleft between the EF and BG loops.

To analyze the GR and c-Jun binding to the canonical motifs, we performed a logistic regression using the generalized linear model (GLM) with the R statistical language.

Nevertheless, we were able to transform a compound once designated as a PAM into an agonist, suggesting it could be binding to the canonical aromatic binding site.

Chromatin plays a critical role in regulating transcription factors (TFs) binding to their canonical transcription factor binding sites (TFBS).