Sentence examples for binding to a β from inspiring English sources

Marginal fluorescent signal changes are observed with THK-265 upon binding to A β aggregates.

CRANAD-3 displayed significant fluorescence property changes upon binding to A β aggregates.

In addition, significant fluorescence signal changes upon binding to A β are required.

One shortcoming is the blue-shift of this probe's emission wavelength to only 625 nm (shorter than 650 nm) following binding to A β plaques.

BAP-1 showed high affinity (Kd=44.1 nmol/L) and a significant fluorescence intensity increase upon binding to A β aggregates.

Furthermore, Zn2+ protects cells by blocking ion fluxes through A β-induced cation permeable channels or competes with Cu2+ in its binding to A β, thereby inhibiting amyloid plaque formation.

Further, unlike most protein protein interactions, which implicate relatively large surface areas, interactions with β are mostly circumscribed to the motif binding to a hydrophobic pocket on β (Georgescu et al. 2008).

However, a study has challenged this view, since it was unable to confirm actin binding to a preformed E-cadherin-β-catenin-α-catenin complex [ 52].

van der Flier et al (2002) have shown that naturally occurring FLNa and FLNb splice variants (var-1) exhibit enhanced binding to a variety of integrin β-tails.

These analogs showed extended emission wavelength and significant reduced binding affinity to A β aggregates compared with DANIR 2c.

BITC also decreased β-catenin binding to a positive cis element of the cyclin D1 promoter and thus inhibited β-catenin-dependent cyclin D1 transcription, possibly through a direct interaction between p65 and β-catenin.