Sentence examples for binding thymine in a from inspiring English sources

A novel conformationally constrained pyridazinone Eag-base PNA-monomer 2 capable of binding thymine in a triplex motif was designed and synthesised.

The novel polymorphism 1747delT, entailing a deletion of a single thymine in a sequence of 11 thymine nucleotides in intron 1, was observed in the SIRS patients.

FdUMP potently inhibits thymidylate synthetase by competitive binding, resulting in a thymine-depleted state ('thymine-less death').

However, only the SOS response was associated with the bactericidal outcome across all tested nutrient conditions, including thymine starvation in a thymine auxotroph.

Recently, a much simpler DNA labeling technique, based on covalent binding of Os VIII bipy complex to thymine residues in a 20-mer tail, was used.

Consider a mutation of a cytosine to thymine in one strand of a DNA in a GC-rich sequence.

The method is based on the difference in mobility of mutant DNA (in the same length) in PAGE that is due to Zn2+ cyclen binding to thymine bases accompanying a total charge decrease and a local conformation change of target DNA.

- An elegant loophole was provided by the idea that 5mC is first deaminated to thymine resulting in a T/G mismatch which, in turn, is processed by thymine-specific DNA glycosylases such as TDG.

None of these triplets regardless of initiation codon included a uracil (thymine in our DNA alignments) at the −1 position.

Because TDG acts on thymine, it needs to be able to discriminate between a regular thymine in DNA (AT) and one that resulted from deamination of 5-meC (GT).

Adsorption of thymine in view of 2-D condensation on a (111) face of a silver single crystal is studied.