Sentence examples for binding template from inspiring English sources

The PET raclopride binding template allows for direct computation of SCR parametric maps after a single normalization step.

One-step co-registration of raclopride binding images to the binding template may also reduce the risks of errors introduced in the multi-step MR-based process.

Taken together, the development of a PET binding template and the use of one-step brain normalization suggest that a total image acquisition time of about 10 to 20 min could be sufficient to establish a reliable diagnosis in patients with parkinsonian syndrome.

In addition, these negatively charged polymers can serve as a binding template for proteins, amino acids, polysaccharides and many cations [ 18- 20].

If the DNA template is crowded with trailing RNA polymerases, nascent RNA molecules will have difficulty in binding template DNA, disrupting R-loop formation (Fig. 1B).

Each residue was treated as an individual unit and was used to align the query protein S with the binding template T. The structural unit consists of a triplet formed by the N C α –C atoms within a given residue.

Other specific binding templates have been exploited to pattern directly biomolecules on gold [84], glass [89], mica [90], oxidised silicon [85] and nickel substrates [87, 91].

With the goal of selective delivery of the HDACi to melanoma cells, we incorporated the benzamide, a high affinity melanin-binding template, into the design of HDACi to generate a new series of compounds 10a-b and 11a-b which display high potency towards HDAC1 and HDAC6.

In this study, we explored a novel series of five and six membered monocycles as alternate hinge-binding templates to replace the 6,5-fused imidazopyridazine core of ponatinib.

The fragment transformation method was used to identify structures within query proteins that resembled the ligand-binding templates.

More recent efforts have identified other inhibitors of RIP1 kinase activity, but these are 'traditional' hinge-binding templates and also inhibit a varying number of other kinases.