Sentence examples for binding targets that could from inspiring English sources

What has changed is that Europe is now less inclined to go it alone and take on binding targets that could put it at an economic disadvantage, while at the same time "governments in many countries realise that tackling climate change is an inevitable requirement and don't want to miss out," says Dickinson.

We reported the number of predicted binding targets that could be verified by corresponding transcription factor ChIP data from any tissues or cell lines where available.

The number and type of aligned residues were used to classify the binding site local conservation, both in terms of sequence coverage (percentage of binding site residues in the original target that could be aligned to the pathogen sequence) and identity (percentage of identical residues among the aligned binding site residues).

The p110αEEE545K/p85α Cdc42-binding interface may rep110αEEE545K/p85α Cdc42-bindingat could interfaceI3Kα E545K signalling without affecting wild-type PI3Kα signalling in non-tumayrepresent

Many infections will have overlapping epitopes and potential drug-binding targets that will be uncovered through basic research and development.

Our results suggest novel mechanisms of PTPA in PP2A activation with structural economy and a unique ATP-binding pocket that could potentially serve as a specific therapeutic target.

For example, in response to outbreaks of cryptosporidiosis in 1995 and 1997, new regulations were introduced in England and Wales, which required testing and reporting against legally binding targets for Cryptosporidium concentrations that could be found in treated drinking water [ Drinking Water Inspectorate (DWI) 1999].

Subsequent albumin binding in the circulation is thought to buffer changes in the effects at target tissues that could otherwise arise from variability in absorption rate.

In addition, residues outside the main ATP-binding cleft have been identified that could be targeted to increase specificity and potency.

Secretary of State John F. Kerry was adamant in the days before the conference that the U.S. could not commit to legally binding targets, in part because that could require approval by the Republican-controlled Senate, which has soundly opposed the Obama administration's climate goals.

This region contains three putative Sp1 binding sites (Sp1-1, Sp1-2, and Sp1-3) that could be potential targets of regulation by methylation [ 11, 12, 21– 23].