Sentence examples for binding surfaces of the from inspiring English sources

Although the actin binding surfaces of the bridge element are not directly blocked in this model, the trans interaction could lead to autoinhibition by at least two mechanisms.

As such, there is very little overlap between the DH domain binding surfaces of the SH3 domain from Asef and SH3(E) from intersectin-1L, suggesting that these GEFs utilize distinct mechanisms of autoinhibition.

In both models, engagement of the DAD by the N-terminus is incompatible with actin filament formation on the FH2, and in one model the actin binding surfaces of the FH2 domain are directly blocked by the N-terminus.

This manuscript by Gupta et al. compares membrane interaction properties and channel binding surfaces of the ASIC1-targeting toxin PcTx1 with GxTx-1E, a toxin targeting potassium channels.

The objective of this study was to compare membrane interactions and channel binding surfaces of the voltage-sensor toxin GxTx-1E and the ASIC toxin PcTx1.

It remains unclear how Fe-S cluster target proteins are identified, because the process seems to be selective and might depend on specific interactions between apoprotein targets and binding surfaces of the chaperone co-chaperone chaperone co-chaperonealong the extensive potential interacomplexrea particularlythe unusualonglarge and disthectivextensivenus of HSC20 (Kampotential Crainteraction

Kobayashi, K. et al. Identification and characterization of the RNA binding surface of the pentatricopeptide repeat protein.

We hypothesized that a peptide designed to resemble the binding surface of the H-helix may serve as an effective disruptor of EGFR dimerization and activation.

Additionally, the extended structure endows a more hydrophilic binding surface of the R-configured peptide to facilitate its capture by its targeted protein.

Development of small molecule inhibitors for TLR9 remains largely empirical due to lack of structural understanding of potential TLR9 antagonism by small molecules and due to the unusual topology of the ligand binding surface of the receptor.

A ligand multimerization problem that would yield suboptimal affinity resins, caused by a cysteine residue present at the binding surface of the Affibody ligands, could be circumvented by the generation of second-generation Affibody ligands (having cysteine to serine substitutions).