Sentence examples for binding surface of both from inspiring English sources

Thus, CoA may trigger a conformational change that disrupts or unsettles the binding surface of both coactivators and corepressors, producing the characteristics of a neutral antagonist.

Whereas most DNA-binding proteins seem to use a charged surface rich in lysine and arginine residues to bind backbone phosphates, the DNA binding surface of OGG1 is nearly charge neutral.

Kobayashi, K. et al. Identification and characterization of the RNA binding surface of the pentatricopeptide repeat protein.

Right, binding surface of hPD-1 for hPD-L1 or pembrolizumab.

Right, binding surface of hPD-L1 for hPD-1 or avelumab.

CBP contains 9 of the 11 key amino acid residues present on the substrate binding surface of CBP21 (Fig. 3).

NMR titration experiments mapped the binding surface of the hSRI domain to helices 1 and 2, and Biacore binding studies showed that the domain binds preferably to [Ser-2 + Ser-5]-phosphorylated CTD peptides containing two or more heptad repeats.

The free and complex states of DHBDAXX are well superimposable without clear conformational change (Fig. S2D), suggesting that the ATRX binding surface of DHBDAXX is largely preformed.

Residues constituting the ATRX binding surface of DAXX are highly conserved among vertebrate species ranging from zebrafish to human (Fig. 1E and 1F), highlighting their functional consensus.

The βγ binding surface of Gs α is largely conserved in sequence and structure to that of Gi α, whereas differences in the surface formed by the carboxyl-terminal helix and the α4-β6 loop may mediate receptor specificity.

The DH domain binding surface of SH3(E) does not overlap with the PxxP-binding groove (figure 8).