Sentence examples for binding studies which have from inspiring English sources

Because of these and other mitigating factors, in vitro binding studies, which have mostly been performed on nucleosomes reconstituted in vitro on artificial DNA sequences, need to be complemented by in vivo experiments when considering the effect of specific nucleosomes on transcription factor binding [14].

Based on this and the binding studies which have shown strong affinity between BMPs and both N- and C-terminal vWC domains [ 18, 23], the BMP dimer is predicted to sit in the cleft.

Multiple beads binding to the cell has been considered in this study, which has not been reported in literature till date.

These findings have been corroborated by immunolocalization and radioligand-binding studies, which showed a similar distribution of 5-HT6 receproteinotein in the rat CNS [ 8, 9].

The present protocol also suggests that MHC class I protein binding as well as notch binding, both of which have hitherto not been studied in the context of breast cancer as more specific functional subgroups of receptor binding which are deserving of more study since both terms may provide insight into receptor binding activity during breast cancer metastasis.

The sequence of this binding site does not resemble any known ATP binding sites, which have much higher binding affinities.

The lack of experimental OR structural information has prompted many computational OR studies, several of which have been carried out on aldehyde-binding ORs.

Any binding site which had a p < 0.01 was annotated as a potential miRNA binding site.

The high-resolution binding site data from a large number of RBPs will benefit investigations on the coordination and competition of RBP binding, which has not been extensively studied.

In comparison with other GlcNAc-binding lectins, AAL-2 performed better than the well-known GlcNAc-binding lectins WGA and GSL-II, which have been used widely in glycan studies for their high GlcNAc-binding selectivity.

We identified endogenous peptide fragments of Retinol-binding protein 4, which has been previously studied in ovarian cancer (using proteomic 2-D electrophoresis), and was suggested to have potential as a diagnostic or prognostic marker at the protein level [ 20].