Sentence examples for binding studies were used from inspiring English sources

Bmax values obtained from saturation binding studies were used to compare expression levels, showing an approximately 2.4 times higher number of receptors on DU145-PSMA cells (Figure 1c).

Competitive binding studies were used to investigate fhlA220 mRNA binding to Hfq. [5'-32P] HF220 complex was prepared and then incubated with excess of either a proximal surface binder (DsrA), a distal surface binder (A18) or both simultaneously.

The final PK/PD model, incorporating potential variability and uncertainty on scaled human prediction together with a receptor affinity adjustment derived from in vitro binding studies, was used to design the first-time-in-man and the proof-of-concept study.

A full-length cynomolgus gene for TNFSF7, previously isolated for non-human primate binding studies, was used to create stable HEK 293F and MiaPaCa-2 transfectants for antibody screening and in vivo studies, respectively.

In addition to the determination of central monoamine concentrations, quantitative radioligand receptor-binding studies were used to examine the effects of long-term administration of imipramine and AV-extract on β-adrenergic binding in rat frontal cortex.

The "common binding rule" assumption of QSAR studies was used and expanded to posit the existence of common rules governing drug-target interaction which could be learned from large-scale drug-target interaction data.

In addition, binding studies were conducted using [125I]-BH-CCK-8S [125I]-BH-CCK-8S [125I]-BH-CCK-8S [125I]-BH-CCK-8S

Cellular uptake, internalization and membrane binding studies were performed using t MCF-7 ATCC® MCF-7 ATCC®ells.

Competitive binding studies were performed using purified FR to determine its affinity for O(4 -BFA.The observed IC(50) for O(4 -BFA.Thebrain tumobservedlIC 50ranged form 0.2 tO 1.3 microM for cells grown in media containing 2.3 microM folic acid.

Autoradiograms from ISH and receptor binding studies were analyzed using the optical density readings (grey intensity).

To gain insights into possible interactions between XLF and XRCC4, binding studies were performed using surface plasmon resonance on a BIAcore apparatus (BIAcore, Uppsala, Sweden).