Sentence examples for binding studies using the from inspiring English sources
Binding studies using the selective cannabinoid CB1 receptor antagonist, [3H]SR141716A, indicated the presence of the specific binding site.
In vitro binding studies using the sera from patients injected with 131I-labeled OC 125 F(ab')2 suggest that circulating CA 125 could interfere with the tumor uptake of the labeled antibody.
The affinity of an antagonist can be determined experimentally using Schild regression or for competitive antagonists in radioligand binding studies using the Cheng-Prusoff equation.
This was established in binding studies using the full size OpuA protein in a detergent-solubilized state as well as the isolated SBD domains expressed as soluble protein (OpuAC).
To understand better the regulation of SNF1 by ADP, we did a series of binding studies using the phosphorylated, active form of the enzyme.
These structure snapshots are consistent with our binding studies using the isolated CBM and KD, in which cyclodextrin strongly reduced the interaction with non-phosphorylated CBM, but only weakly reduced the interaction with phosphorylated CBM.
Ints6 also interacted with GST-Spt5 in binding studies using insect cells expressing the 12 Integrator subunits individually (Fig. 1d), indicating a direct interaction between these proteins.
Binding studies using surface plasmon resonance indicated that the conjugate binds to the HER2 extracellular domain with high affinity compared to compound 5 or DOX alone.
In conclusion, a fluorescent analogue of CGP 12177 displayed similar pharmacology to its parent compound and could be used not only in functional studies, but also in binding studies using live cells to probe the secondary, low-affinity 'CGP 12177' site of the β1-adrenoceptor.
Decapeptide binding studies using pooled sera reproducibly identified the same 9 epitopes.
Competitive binding studies using purified FR confirmed that the IC 50) for O(4 -BFA is approximately 180 times greater than folic acid, i.e., it has a very weak affinity for FR.These results indicate that O(4 -BFA has potentislly broapproximatelyinactivator of AGT as its use is not limited to tumors expressing high levels of FR.
