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Regarding proof that an h-site does or does not exist, I agree that binding studies must be performed to see how many ATPs actually bind to R1, but such studies may be difficult, as evidenced by the fact that they have not yet been performed.
Similar(59)
More studies must be performed to determine the relationship between the presence of a specific receptor with low or high binding affinity for Tf and Fe necessity.
Future mechanistic studies must be conducted.
In vitro binding studies must therefore be complemented with in vivo measurements.
The study must be completed by January 2018.
Limitations of our study must be considered.
Limitations of this study must be recognized.
Limitations of the study must be highlighted.
(3) Study must be case control design.
The imaging study must be feasible.
Limitations of the study must be considered.
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