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Locked nucleic acid nucleotides could be included in the MTP sequence to increase binding strength and specificity, and to decrease non-specific amplification [ 49].
The incorporation of locked nucleic acids (LNAs) into oligonucleotide primers has been shown to increase template binding strength and specificity for DNA amplification.
In the present study MBs were characterized under AmpliDet RNA conditions, with respect to probe stability, binding strength, and specificity, which led us to propose a design method, useful for probe design for AmpliDet RNA and adaptable to microarrays.
The binding strength and specificity were analyzed by using ELISA with scFv antibodies against nmAb-KT.
Such classes might differ in their co-factors and/or binding strength and specificity (e.g., canonical vs. full-spectrum motifs).
We analyze the effects of GAG length and sulfation patterns in binding strength and specificity, and the influence of GAG binding on IL-8 dimer formation.
Similar(54)
Binding of the CBD differed between chitin on Au versus chitin on PS in terms of binding strength and binding specificity due to a less homogenous structured chitin-surface on Au in comparison to chitin on PS, despite a similar thickness of both chitin layers in air and after running buffer over the surfaces.
As compared to that of other lectins, the interaction between wheat germ agglutinin (WGA) and chondrocytic cells was characterised by remarkable cytoadhesion, adequate binding strength and a high degree of specificity for N-acetyl-glucosamine as contained in hyaluronan chains.
In 2011, a simulation study by Martinez-Veracoechea and Frenkel discussed how ligand valency, binding strength, and level of receptor expression affect specificity of binding.
The binding strength and the number of binding sites were determined at different ionic strengths.
Such double binding markedly increases the strength and specificity of the interaction [9].
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