Sentence examples for binding strength and affinity from inspiring English sources

The target 5' GGGGGGGGG 3' has most negative docking score with very high binding strength and affinity complementing our simulation studies which exhibit relatively high stability.

The selection of the T-cell repertoire which is essential for establishing self/non-self discrimination of immune recognition occurs in the thymus, and is based on the binding strength (affinity) of the TCR for peptide MHC complexes that are presented by epithelial and bone-marrow-derived antigen-presenting cells.

Time-resolved quantitative data about the kinetic mechanisms of the competition, provide information beyond the fact that competition occurs, including the relative binding strength or the affinity of the competitor itself.

Modulation of an interaction by modification of multiple residues even allows for rheostatic control of binding strength, where the affinity for an interaction partner is gradually altered by multiple modifications that additively enhance or diminish the interaction.

Affinity is a binding strength between an antigenic determinant and an antigen-binding site, and complementarity-determining regions (CDRs) account for formation of the antibody binding pocket.

Another limitation of Fab fragments pertains to the fact that they are monovalent, often resulting in the loss of functional affinity and reduced binding strength compared to e.g. Fab2 or IgG.

The affinity constant (A = 1/K) and binding strength (S = A × σ) were estimated.

Conversely, antibodies selected from in vitro libraries can be produced more rapidly but are typically of lower binding strength due to the lack of affinity maturation.

An antibody can recognize its antigen, and can evolve toward the immunogen to increase binding strength, in a process referred to as affinity maturation.

Monovalency often results in the loss of functional affinity and reduces the binding strength of the Fab or Fab' fragment as compared to the F ab' 2 or IgG [39, 40].

In that study, the maximum adsorption capacity was 42 mg protein g−1 lignin, the affinity constant 1.5 ml mg−1, and the binding strength 64 ml g−1 lignin.