Sentence examples for binding step but not from inspiring English sources

Taken together, these findings suggest that the active site residues forming the small pocket are mainly engaged in the binding step but not significantly involved in the catalytic step, which may provide insights into how to design a rational strategy for engineering of the small pocket to relieve the steric constraint toward bulky substituents.

H66, which strongly contributes to the specificity of the esterified amino acid in the binding step, appears not to contribute to stabilizing the complex prior to release.

It was clear that the ATP-binding step does not set the overall rotational cycle at 1 mM ATP at 4°C; thus, the temperature-sensitive reaction is not an ATP-binding reaction.

Cyclin A binding prevents PRMT1 binding but not PRMT5.

Handrail usage influenced the variability of step length and step width, but not of step time.

The measure was described by supporters as a critical, but not binding, step to position the city to take advantage of badly needed revenues.

We reasoned that the dTTP Km of T7 helicase translocating on ssDNA would be the closest estimate of the dTTP Kd of the base-captured state of the leading subunit, because the base-capture and dTTP binding steps on ssDNA are not limited by base pair separation.

Since the initial promoter binding step (formation of RPi, Figure 5A) is not affected by the σ W433A substitution, we surmise that RPi does not feature the stacking interaction formed by W433A on the T−12 nt) base (exposed by the flipping-out of A−11 nt)).

The license is binding, but not heavy handed.This is a big practical step to freeing institutional holdings which are, in theory, already freely accessible.

Whichever route is chosen, the findings are binding on management, but not on the employee.

Two-step binding is not inconsistent with the structure, but the nearly identical affinities observed for each binding event suggest positive cooperativity.