Sentence examples for binding stability of proteins from inspiring English sources
While determining the binding stability of proteins across all possible DNA structures is not feasible, it is in principle possible.
A lack of cdTMPRSS6 in the conditioned medium of TMPRSS6 Y141C -transfected TMPRSS6 Y141C -transfecteda lacells proteolytic auto-activation of the mayateitherteindicatecreased binding stabilack of the catalytic domain to the rest of the proteolytice to the formation of an extra disulfide bond in the Y141C-mutated profein.
The biotin-binding ability and stability of protein constructs were detected by SDS-PAGE and immunoblot analysis.
In silico site directed mutagenesis has been widely used to identify critical residue(s) for binding of a ligand/substrate or stability of protein.
In those systems, Runx proteins function as heterodimers by forming complexes with CBFβ, a non-DNA-binding cofactor that enhances the DNA binding affinity and protein stability of Runx proteins (Adya et al., 2000).
In many cases, ion binding and protein binding are primary approaches for the maintenance of the structural and functional stability of protein molecules.
For low-resolution models, total energy of the master subunits was employed, while for high-resolution models, we also took the interface energy into account as it is an approximation to binding energy [ 24, 25] and depicts the stability of protein docking.
The importance of compensatory changes can be justified in terms of maintaining the stability of protein complexes and/or the specificity of their binding to other proteins.
This helps to measure the stability of protein (T m) in the presence and absence of a small-molecule compound to determine the differential shift in protein stability (ΔT m) upon compound binding.
Since one tryptophan is located within the binding pocket, expanding the natural genetic code by incorporation of FWs in the protein might affect the binding ability and/or stability of the protein.
CBFβ is indispensable for Runx1 activity in cells of the hematopoietic lineage because of its role in enhancing the DNA-binding activity and stability of Runx1 proteins (Adya et al., 2000).
