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For hiomt in situs, probe binding specificity was improved by carrying hybridization and post-hybridization washes at 62 ° C and by using a lower SSC concentration for the last post-hybridization washes (0.1x SSC instead of 0.2x SSC).
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In their series, specificity was improved from 96.6 to 100%.
Actin binding specificity was demonstrated by competitive binding experiments and comparative staining of well-known structures.
Similar binding specificity was shown for the parent antibody V5B2 [13].
However, the binding specificity might be improved with multimodal molecular interactions.
Details of binding specificity are provided in SI Figures S5 S7.
Specificity could be improved by using purified antigens.
Specificity of binding to RNA can be improved by targeting two loops by coupling together two small molecules.
Furthermore, combining the molecular modeling with impedance detection, the accuracy, specificity and predictability of the ligands binding to the protein could be improved.
An important potential advantage of our method is improved specificity.
However, the specificity was markedly improved by FS, achieving 75%.
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