Sentence examples for binding specificity that could from inspiring English sources

Information gained from such studies may enable the design of Evasins with defined chemokine binding specificity that could be therapeutically useful in inflammatory and infectious diseases, and cancer.

We have observed that docking heparin/heparan sulfate disaccharides to the IL-8 heparin-binding site (Kuschert et al. 1998) does not reveal binding specificity that could help suggesting a most probable binding pose for longer GAGs (data not shown).

These results, together with our previous demonstration of non-cytotoxic cobra CTX A5 in targeting αvβ3 integrin, suggest that cobra venom consists of several non-RGD toxins with integrin-binding specificity that could perturb wound healing in snakebite victims.

The presence of a B3 DNA-binding domain together with a WRKY domain and domains from intracellular resistance proteins suggest that this R protein has at least two different DNA-binding domains with different cis-acting element specificities that could be responsive to both biotic and abiotic stresses.

Several polar residues are also present in the Spy0129 binding groove that could account for its altered specificity; Tyr124 and Ser219 in Spy0129 replace Ala118 and Ile182 in SaSrtA.

The putative signal of secretion, the structural similarities with these different proteins sharing the DC-SIGN domain and its mannose binding specificity suggest that PdC-Lectin could interact with zooxanthellae mannose ligands to mediate symbiont acquisition as it was described for the F. scutaria/ Symbiodinium model [ 64].

Finally, Kumar and colleagues30 found that the mobility of soluble transcription factors depends on their binding specificity: those that make less specific contacts move faster.

It is plausible that a minor mutational event that alters their target binding specificity could facilitate a swap of regulatory programs, and lead to broad physiological and phenotypic effects mediated by their specific targets.

Based on computational results, the binding capacity showed that the highest binding specificity toward Tr could achieved when using pyrrole (PY) as the monomer in dimethyl sulfoxide (DMSO) solution to form a polymer matrix.

But methods combining DNase digestion data with TF binding specificity information could potentially be used to survey the locations of many TFs in the same experiment, provided such methods permit reasonable levels of sensitivity and specificity.

This suggests that these proteins could have dual Ub-SUMO binding specificity and that in higher eukaryotes the SIM function is substituted by PIP motif.