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Isotope-edited spectroscopic analysis and binding specificity of these complexes provides information about specific enzyme transition state contacts.
Breast cancer cell surface is decorated with CS-GAGs and due to tumor-specific expression patterns of chondroitin sulfotransferases and PGs, the composition and binding specificity of these polysaccharides differ from those of normal tissues.
The binding specificity of these antibodies was verified by immunohistochemistry on cryo sections of the OE of eNOS deficient mice (eNOSdelMu).
The binding specificity of these anti-V3 scFvs was checked with phage from the 24 well plate and PEG precipitated purified phage.
However, binding specificity of these ATFs is usually degenerate, can be difficult to predict and the complex and time-consuming design and generation limits their applications.
Further, we have elucidated the characteristic motifs of the piRNA clusters which might provide a clue regarding the target binding specificity of these clusters.
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Therefore, changes in these sites may influence the binding specificity of the protein.
Relatively, these sequences are less important to the binding specificity of the encoded protein [ 22].
These SNPs might serve as variants which affect the binding specificity of the Cbf gene family.
Recent structural and biochemical studies have focused on understanding the glycan receptor binding specificity of the 1957-58 pandemic H2N2 HA.
This result further demonstrates the binding specificity of the RBFOX1/2 binding motif and suggests that the SRSF1 motif would not efficiently interact with RBFOX1/2 proteins.
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