Sentence examples for binding specificity is very from inspiring English sources
However, we report here that orthologous pairs of TF DBDs almost invariably bound to the same DNA sequences, indicating that the binding specificity is very deeply conserved.
With high sensitivity, specificity is very low.
Substrate specificity was very high for formaldehyde.
Actin binding specificity was demonstrated by competitive binding experiments and comparative staining of well-known structures.
Similar binding specificity was shown for the parent antibody V5B2 [13].
Details of binding specificity are provided in SI Figures S5 S7.
The reviewers also found that our key finding that "The key finding is that Drosophila and Mammalian TFs with similar protein sequences have highly similar DNA binding specificity…" is very significant".
This analysis revealed that TF binding specificities are highly conserved between Drosophila and mammals, and that for orthologous TFs, the similarity extends even to the level of very subtle dinucleotide binding preferences.
However, this is obviously not applicable to AdpA; the DNA-binding specificity of AdpA is very low, and AdpA can bind to >1500 sites (including many 'apparently irrelevant' sites) across the chromosome.
Any binding which cannot be opened is suitable; a spiral binding is very convenient.
