Sentence examples for binding specificity is determined from inspiring English sources

Much more commonly a small collection of binding sites is obtained and from them a model for the TF's binding specificity is determined.

Experiments of mutant proteins demonstrated that binding specificity is determined by the core basic region and the hinge region independently, and the two regions have an additive effect on DNA-binding specificity.

The major advantage of this system is that only one dCas9 activator is required to activate multiple genes individually or simultaneously and that its DNA binding specificity is determined by sgRNAs, which are designed based on simple RNA/DNA complementarity.

The targeted DNA binding specificity is determined by TALE repeats through protein DNA contact in TALEN-mediated genetic modifications, whereas in the case of a CRISPR/Cas9 system, the specificity is determined by the gRNA binding through RNA DNA contact (Miller et al., 2011; Zhang et al., 2011; Jinek et al., 2012).

Cytokine binding specificity was determined using a BIAcore X biosensor (Biacore, Uppsala, Sweden).

We obtained 14 different peptide aptamers, whose binding specificity was determined using a yeast two-hybrid mating assay.

Nucleotide-binding specificity is determined not only by possible contacts with nucleotides but also by steric exclusion of interactions with alternative nucleotides (reviewed in [ 25]).

Binding affinity and specificity was determined using direct binding assays with toxoid-coated and toxin-coated microspheres as described in the methods.

The relative binding affinity of TAs was determined by the amount of fluorescence detected on the cells based binding assay and the specificity was determined by the extent of doxycycline dose dependent effect seen on TA binding.

The KIR binding specificity is largely determined by the amino acid at position 80 of HLA-C [20].

This figure clearly shows that binding specificity is primarily determined by the structural family of the TF.