Sentence examples for binding specificity for these from inspiring English sources

We used the computational protein design approach to modify CaM binding specificity for these two targets.

In contrast, flexible amino acid residues have rarely been investigated, even though these residues may affect the binding specificity for the cellulose of each biomass.

As a pair, the central repeat regions of TALENs determine the DNA binding specificity for the two sub-target sites; and the dimeric non-specific FokI cleavage domains cause a DNA double strand break (DSB) between the bound sequences.

To overcome these challenges, we have engineered a tetravalent bsAb with bivalent binding specificity for the CD20 and CD3 antigen in an immunoglobulin G (IgG) format.

The genetically engineered anti-CD20 scFv and GPI-tagged derivative have binding specificity for the CD20 antigen.

Using yeast surface display to screen a designed library of Bcl-xL variants, we successfully identified a protein with ~ 1000-fold improvement in binding specificity for the BH3 region of Bad over the BH3 region of Bim.

The resulting Gal4-VP16 fusion protein retains the Gal4's DNA binding specificity for the UAS but is a vastly more efficient transcription factor.

It is a highly potent α2 adrenergic agonist with a remarkable binding specificity for the α2 adrenoceptor.

AKAPs are classified according to binding specificity for the PKA regulatory subunits; RI-, RII- or both RI and RII PKA regulatory domains (dual specific) [ 12].

Although most substitutions will likely disrupt binding specificity for the current target site, a few may create new interaction sites leading to the emergence of novel functions.

Residue 31 in Rap and Ras is a key residue for determining the binding specificity for downstream effectors of these two closely related small GTPases (Nassar et al., 1996).