Sentence examples for binding specificities was generated from inspiring English sources

Recently, a dataset containing a large number of these binding specificities was generated using protein-binding microarrays (PBM) (Weirauch et al., 2014).

When a new TF with the same DNA-binding specificity is generated by gene duplication, new pairs of TFs and their target genes also arise, causing harmful "cross lines" through the DNA-binding sites that were previously neutral features.

In one example, a TNF-α binding peptide with Kd = 90 nM and high target specificity was generated.

Conversely, a large collection of Drosophila TF binding specificities has been generated using bacterial one-hybrid assay (B1H; Noyes et al., 2008; Zhu et al., 2011; Enuameh et al., 2013).

Thus, TRAPs with novel binding specificity can be generated by mixing-and-matching TRAP pockets that have been selected to bind particular amino acids rather than performing new selections for every peptide target.

Then, a binding pocket was generated.

Actin binding specificity was demonstrated by competitive binding experiments and comparative staining of well-known structures.

Similar binding specificity was shown for the parent antibody V5B2 [13].

It is relevant to note that het-c, the antagonistic locus of het-d and het-e in VI, also displays signs of fast evolution [ 29] suggesting a co-evolution with the hnwd genes, thus new binding specificities might also be generated through evolution of het-c.

A recombinant C. parvum DNA-binding protein domain from a putative ApiAP2 transcription factor [CryptoDB: cgd8_810] was generated and tested on PBMs to determine its binding specificity.

Details of binding specificity are provided in SI Figures S5 S7.