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The binding specificities of all receptors were varied between individual runs of the program.
We report here the binding specificities of all human and mouse ETS-family TFs.
Similar(57)
Given the relatively similar DNA-binding specificities of all the ETS-family members, an important question is whether the specificity of binding comes from the observed relatively small differences in protein DNA binding affinity, or whether direct protein protein interactions, or more complex chromatin-mediated effects dominate.
To determine the binding specificities of the ETS factors, we first cloned all human and mouse ETS DBDs and human ETS full-length cDNAs.
These predictions, however, depend on the availability of information about the DNA-binding specificity of ideally all TFs encoded by a genome.
In this research, we predicted sugar-binding specificities for all mentioned proteins and for a large numbers of their homologs.
In order to confirm the binding specificity of avidin to biotin, a second experiment was performed.
The binding specificity of bead binding was determined following protocols described previously [8].
All these elements taken together strengthen the hypothesis that PdC-Lectin is functional and shares the mannose binding specificity of the human DC-SIGN CRD.
Cooperative DNA binding, via self-association, often increases the DNA binding specificity of a protein.
Spotting the peptides as a microarray allows for comparison of TNF-α binding specificity across all variants in a single experiment.
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