Sentence examples for binding sites would have from inspiring English sources

The analysis based on the conservation of individual binding sites, however, does not address the question whether a promoter or enhancer, which typically have multiple binding sites, would have conserved functionality or not, as the gains and losses of binding sites in the neighborhood may compensate each other so that the overall affinity remains largely unchanged [56], [64], [65].

Multiple paralogs, each with multiple binding sites, would have drastically increased the number or specificity of cargo binding, and therefore many have been selected for.

Under those conditions, our simulations suggest that degradation of sites would have a major impact on VEGF availability for receptor binding.

Using conventional EMSA, four labeled-oligonucleotides based on each of these putative sites would have been required to examine which, if any, were involved in Sp-1 binding.

If these were rare and/or stable binding sites, this would have a major influence on the dynamic parameters measured.

The binding sites would not only reveal mRNA targets but would show GQ motif consensus if that's really the in vivo binding site for Aven.

Since the structure fluctuates in the region coinciding with the α1β1 loop, which was our proposed docking binding site, it would have been unreasonable to dock to the single domain conformation taken from the crystal structure of the dimer, or to dock to the averaged structure of the MD trajectory.

A protein binding site would be an attractive hypothesis.

While we agree that mutating the receptor-binding site on BLyS would have been a valuable way to address the importance of signalling through BLyS receptors, when these studies were carried out, the receptor-binding site on BLyS was not defined.

The approach provides site-specific information regarding the binding interface that would have broad application in the field.

The binding of K+ to cation-dependent sugar transporters may open available binding sites for sugars that would have been closed prior to cation binding.