Sentence examples for binding sites with an from inspiring English sources

A molecular-mechanics potential is used to reconstruct the coordinates of various binding sites with an average root-mean-square error of 0.61 Å and to reproduce known ligand-induced side-chain conformational shifts.

Saturation binding experiments, performed in the temperature range 4 30 °C by using the high affinity purinergic agonist [3H]αβmeATP, revealed a single class of binding sites with an affinity value in the nanomolar range in both cell lines examined.

Palonosetron exhibited a concentration-dependent decrease in binding sites with an IC50 of 0.38 ± 0.02 nM, indicating that down-regulation occurs within a concentration range very similar to that of competition binding (dose ratio of 1.7 between the two measurements).

DNA binding assays determined binding sites with an AGT core sequence for SUP (C1-1i) [ 30], like in earlier reports for ZPT2-1 (or EPF1) and ZPT2-2 of petunia (C1-2i) [ 38].

The core (total size 22.3 Mbp, 73% probe coverage) housed 38% (362) of ORC1/CDC6 binding sites, with an average spacing of ∼130 Kbp between adjacent members of 170 "unique" binding sites (those closer than 10 Kbp were grouped).

We generated and analysed 21 903 762 and 21 709 675 36-bp single-end read tags and identified a total of 17 431 and 13 457 pol II binding sites with an estimated false detection rate of P < 0.001 (Tables  1– 3) in Ramos and BEAS2B cells, respectively (Supplementary Fig. S1E G).

Thus all genes with specificity 3 bind to all binding sites with a specificity 3, possibly connecting multiple source genes with various target genes.

DNA origami templates, modified to have DNA binding sites with a uniquely coded sequence, were adsorbed onto silicon dioxide substrates.

The macroscopic cooperative constant ρ was then determined to be 0.333 (ρ = 4β2/β12), which indicates that the binding model is either two independent binding sites or two identical binding sites with a negative cooperativity.

Saturation isotherms constructed in Hepes-Tris buffer best fit a model of a single independent population of binding sites with a dissociation constant of 1.6 microM and maximum density of 16 pmol/mg protein.

Genome-wide studies have identified that the majority of CTCF binding sites belongs to a set of nonpalindromic CTCF binding sites with a consensus sequence referred to as M1 (Kim et al., 2007; Schmidt et al., 2012).