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Increasing evidence has suggested that bispecific and multivalent antibodies which have more antigen binding sites will improve their immunogenicity.
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Increasing the number of HARP sites will improve geographic and demographic representation.
NCaBD containing two Ca2+ binding sites will need to be fit with a two binding site model.
Thus, signal measured in regions associated with low density of binding sites will consist of a larger fraction of signal from blood than that measured from a region with a high density of binding sites.
Also gross chromosomal alterations not affecting closely located primer binding sites will not be reflected.
Specification of the drug binding site will result in docking around the given three-dimensional coordinate.
Finally, Detection of Binding Sites will be employed for binding site detection.
More accurate models of sequence specific nucleosome binding will improve the accuracy of these predictions.
Developing disused sites will both improve our towns and cities, and help us safeguard the countryside.
Although the interactions with binding sites improve, the changes are very small, except for the reduction in atomic clashes.
More recently, inhibitor design has considered secondary binding sites (exosites) to improve specificity.
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