Sentence examples for binding sites which has from inspiring English sources

The nanowire's response mechanism to hydrogen peroxide is also discussed in terms of the synergistic activity of the bimetallic binding sites, which has important implications for a better design of functional nanowires as sensing materials for a wide range of applications.

Under this scenario, one would expect MBG to be located close to DCC binding sites, which has been observed for head and brain (Chang et al. 2011; Catalán et al. 2012).

To predict the putative STAT3 binding sites on precursor region upstream of the miRNA sequence, we considered the list of miRNAs predicted to have putative STAT3 binding sites which has been recently reported [ 16, 17].

This means, that the adsorption of GTFs to a multitude of oral bacterial species may only work with the existence of universal binding sites, which has to come along with some degree of conservation of the gtf-gene for proper biofilm formation in the human oral cavity.

Its domain IV, which consists of a tandem of immunoglobulin-like modules (IG2-IG15), is rich in such binding sites, which have been mapped to different modules obtained by recombinant production.

The sequence of this binding site does not resemble any known ATP binding sites, which have much higher binding affinities.

Both of these approaches suffer from the inability to model and detect low-affinity binding sites, which have recently been shown to be abundant and functional.

For example, in Drosophila, the cone-specific Pax2 enhancer carries barely-conserved TF binding sites, which have been shown to possess similar enhancer functions in transgenic assays [31].

The main advantage of our method is its ability to predict multiple binding sites which have been predictable only by expensive algorithms [ 1, 13] so far.

In addition, CENTIPEDE uses a stringent cutoff (based on PWM matching) to define putative binding sites, and thus may lose significant information in relatively weak binding sites, which have been shown to be collectively important for TF binding [ 71].

Some type of cooperativity among TFs, however, was an important component of the Gertz models and could explain the functionality of weaker binding sites, which have been argued to be prevalent in the yeast genome (Tanay 2006).