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The 150bps sequences at the Atf1/Pcr1 binding sites were used in DNA-binding motif discovery.
Multiple copies of the miR-312 binding sites were used to increase the probability of efficient miR-312 binding.
Validated CoREST and REST promoter binding sites were used as positive controls, while a non-target gene promoter was used as a negative control.
Although the entire set of ZNF274 binding sites were used for the motif analysis, the two long motifs shown in Figure S8, panel A are highly enriched in the top 100 ranked peaks.
Only PWMs generated from the collections of vertebrate DNA binding sites were used.
The same primer binding sites were used as previously published [ 8].
Similar(46)
Experimental and predicted binding sites are used in molecular docking with the default and optimized box sizes.
As for ligand-based methods, structural descriptors of ligand-characterized binding sites are used to transfer the ligand annotation of putative targets to the query binding site.
A similar result was observed when 450-stop, which did not contain any predicted tensin binding sites, was used (Fig. 2B).
A basis behind FBDD is "pharmacophore", by which common atom conformations in binding sites are used for designing multi-targeted drugs [6], and several pharmacophores over different protein families are now known [15].
In this paper, the terms "motifs" and "transcriptional factor binding sites" are used interchangeably.
More suggestions(15)
binding sites were predicted
binding profiles were used
binding intervals were used
binding sites were eliminated
binding peaks were used
binding simulations were used
binding sites were examined
binding affinities were used
binding sites were implicated
binding data were used
binding sites were blocked
binding sites were required
binding sites were studied
binding sites was used
binding sites were enriched
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