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In the brain stem the highest [3H]sumatriptan binding sites were seen in the substantia nigra, the trigeminal nucleus, nucleus of the tractus solitarius and periaqueductal gray [43].
Five type B RBP1 binding sites were seen in this work: two in exon ms2, another two in intron is2, and one in intron is3 (Fig. 4).
A greater number of intronic binding sites were seen for H3K4me1 (54.3-56.7%) as compared to H3K27me3 (36.8-38.1%), and fewer sites were noted in distal intergenic regions for H3K4me1 (28.9-37.6%) as compared to H3K27me3 (50.5-51.5%) (Additional file 8: Figure S2).
Although the numbers of sex-biased genes varied depending on the mapping software and the statistical method, the main results (a significant enrichment of MBG on the X chromosome; MBG significantly closer to DCC binding sites) were seen with all methods (supplementary table S2, Supplementary Material online).
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Some clustering of binding sites was seen in the 10 kb region immediately upstream of duf.
A similar pattern of binding sites was seen for H3K4me3 and RNA Pol II in the two cell lines, particularly in exons (range 2.7-3.1 2.7-3.1anslated regions (range 2.8-4.0%) and introns (41.2-41.4% for RNA Pol II and 49.2-51.9% for H3K4me3).
Furthermore, 1 or 2 bp changes in a 14 bp binding site were seen to alter dissociation rates for 2 and 3 by as much as 30-fold.
Enrichment for the ookinete binding site is seen only in Plasmodium species.
Although no reads were detected nearby the majority of putative PUF binding sites in the 3′ UTR of soybean genes, a bias in favor of the position 3-nt upstream of the PUF binding site was seen.
Another region close to the edge of this 2 kb segment had another larger-than-30 "Hits" peak but no MyoD-binding site was seen.
The abrogation of the Nrg1-binding site was seen to have only a moderate effect on herbicide-induced PDR18 up-regulation when compared with the full effect observed upon Nrg1 deletion.
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