Sentence examples for binding sites were localized from inspiring English sources
More than half of the EWS/FLI1 binding sites were localized to intergenic regions.
Simultaneously, Gal-3 binding sites were localized around the nucleus of proliferating fibroblast, whereas resting cells only had minimal binding sites in the cytoplasm [ 18].
Interestingly, about 35%% of the binding sites were localized at either intronic (24 %) or intergenic regions (11 %), suggesting that Tip60 may also play a role in regulating enhancer activity (see below).
On a genome-wide scale, the LRH-1 binding sites were localized mainly in proximal promoters (24%) and 5'UTR (22%) regions, whereas similar to other nuclear receptors analyzed to date, FXR binding occurs primarily in distal intergenic regions (44%) and introns (32%), with only 10% localizing to proximal promoter [ 14].
Here we show that ETS transcription factors are novel regulators of MCM4 origin, whose binding sites are localized between two divergently transcribing MCM4 and PRKDC genes.
Many CBP binding sites are localized in sites known as HOT sites which are regions in the genome that bind multiple transcription factors [ 7].
(15) For the Axin2 promoter, conserved TCF/LEF binding sites are localized in intron 1,(16) and Simple ChIP Human Axin2 Intron 1 Primers (Cell Signaling, Danvers, MA, USA) were used.
To investigate this mode for transcription inhibition, we have employed a model system in which a PNA binding site is localized between the T3 and T7 phage RNA polymerase promoters, which respectively assume the roles of primary and secondary promoters.
Only one binding event – a ChIP-seq Nanog binding site – was localized directly at the transcription start site, for TU4.
