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Binding sites with >5 residues were outputted, and 54,936 binding sites were extracted, which could bind with 12,138 ligands.
The 978 ATP-binding binding sites were extracted from the sc-PDB database [39] and feature a total of 433 unique proteins among which 110 are protein kinases.
Sequences of axis protein binding sites were extracted from the genome using Python scripts (Supplementary file 2).
Interaction data used to build the human interaction matrix and to classify RBP binding sites were extracted from the AURA 2 database (/ http://aura.science.unitn.it/download/).it/download/
The fungal LSU rDNAs containing the binding sites of both primers were kept and the corresponding segments between the two binding sites were extracted.
Genomic sequence of miRNA cluster and the predicted transcription factor binding sites were extracted from the " Cis-element clusters within BlastZ Aligments" option at the GenomeTraFac [ 44].
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Functional binding sites are extracted by a rapid molecular dynamics shaker.
The coordinates of the binding site were extracted using the co-crystallized ligand, Ibuprofen.
To predict SigB regulon structure in each organism, the SigB HMM and PWM were used to independently scan across all 20 Bacillus genomes, and TUs 3' to a significant binding site were extracted.
In a first step, alternative conformations of a given binding site are extracted from an arbitrary selection of protein structures, e.g. the current version of the Protein Data Base (PDB).
In brief, 1 kb of sequence from each binding site is extracted and filtered for conserved sequences.
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binding sites were detected
binding sites were assigned
binding sites were found
binding sites were sought
binding sites were included
binding sites were compared
binding sites were refined
binding sites were identified
binding experiments were extracted
binding sites were isolated
binding sites were examined
binding domains were extracted
binding reactions were extracted
binding annotations were extracted
binding sites were implicated
binding sites were blocked
binding sites were required
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